METHOD FOR PREDICTION OF RISK OF PERINATAL PATHOLOGY Russian patent published in 2014 - IPC G01N33/53 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to obstetrics and gynaecology, and also can be used by the doctors of the other areas of medicine. Substance of the method: ultrasonography in pregnant women aims at detecting appendage new growths and diagnosing degree I and II foetal growth retardation (FGR). The symptoms observed enable finding out: preeclampsia, thrombocyte (Tr) and leukocyte (WBC) count in complete blood count, total blood plasma protein by biochemical blood assay, A coagulogramma shows activated partial thromboplastin time (APTT) and thrombocyte (Tr) count. A vaginal secretion is sampled and analysed for cytomegalovirus (CMV) by a polymerase chain reaction. That is followed by calculating a prognostic index R by formula R=-1.59K1-0.96K2+1.33K3-0.6K4-1K5-0.009K6+0.003K7-0.03K8-0.007K9-0.04K10+4.78, wherein K1 is appendage new growths - yes - 1, no - 0; K2 - cytomegalovirus - yes - 1, no - 0; K3 - preeclampsia - yes - 1, no - 0; K4 - degree I foetal growth retardation - yes - 1, no - 0; K5 - degree II foetal growth retardation - yes - 1, no - 0; K6 - WBC - leukocyte count in complete blood count (*10³/mm³); K7 - Tr - thrombocyte count in complete blood count (*10³/mm³); K8 - total protein - total protein in biochemical blood assay (g/l); K9 - Tr - thrombocyte count in the coagulogram (*10³/mm³); K10 - APTT - activated partial thromboplastin time (sec) in the coagulogram; 4.78 is a constant. If R is less than 0, a risk of a perinatal pathology is stated. R exceeding 0 enables stating no risk of a perinatal pathology.

EFFECT: improved prediction procedure.

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