STABLE INJECTABLE PARACETAMOL FORMULATION FOR INJECTIONS Russian patent published in 2014 - IPC A61K31/167 A61K47/18 A61K47/20 A61K47/40 A61K9/08 

Abstract RU 2519764 C1

FIELD: medicine.

SUBSTANCE: aqueous solution contains paracetamol, a compound stabilising and dissolving paracetamol in the solution, specified in a group consisting of cyclodextrins, a stabilising compound containing a thiol functional group, and a stabilising compound specified in a group consisting of thiamine salts. Preferentially, the stabilising agents are presented by 2-hydroxypropyl-beta-cyclodextrin, monothioglycerol and thiamine hydrochloride.

EFFECT: aqueous solution of paracetamol is storage-stable for more than 30 days at high temperature.

19 cl, 4 tbl, 4 ex

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RU 2 519 764 C1

Authors

Tseti Julija

Dates

2014-06-20Published

2011-05-18Filed