FIELD: medicine.
SUBSTANCE: aqueous solution contains paracetamol, a compound stabilising and dissolving paracetamol in the solution, specified in a group consisting of cyclodextrins, a stabilising compound containing a thiol functional group, and a stabilising compound specified in a group consisting of thiamine salts. Preferentially, the stabilising agents are presented by 2-hydroxypropyl-beta-cyclodextrin, monothioglycerol and thiamine hydrochloride.
EFFECT: aqueous solution of paracetamol is storage-stable for more than 30 days at high temperature.
19 cl, 4 tbl, 4 ex
Title |
Year |
Author |
Number |
PHARMACEUTICAL COMPOSITION AND METHODS FOR USE |
2017 |
- Li, Yuhua
- Huang, Chiating
- Mao, John
|
RU2719450C1 |
NOVEL DEPOT-PREPARATIONS FOR INJECTION |
2003 |
- Shakh Dzhejmin Chandrakant
|
RU2310450C2 |
COMPOUND ON BASIS OF ARIPIPRAZOLE COMPLEX |
2003 |
- Nerurkar Manodzh
- Naringrekar Vidzhehj
- Dominik Mark
|
RU2342931C2 |
SOFT GELATINOUS CAPSULES WITH HIGH STABILITY, CONTAINING HYDROXYPROPYL-BETA-CYCLODEXTRIN |
2018 |
- Karuchchi, Simone
- Markorri, Mauritsio
- Pontidzha, Marko
- Fossati, Titsiano
|
RU2768630C2 |
STABILISED VORICONAZOLE COMPOSITION |
2011 |
- Zaludek Borek
- Zatloukalova Libushe
|
RU2566262C2 |
METHOD FOR OBTAINING AMORPHOUS CO-EVAPORATES OF CLADRIBIN WITH CYCLODEXTRINS |
2021 |
- Babij Vladimir Evstakhievich
- Konoplyannikov Ivan Georgievich
- Zabudkin Oleksandr
- Mata Vladimir
|
RU2758436C1 |
PHARMACEUTICAL COMPOSITION FOR INJECTIONS |
2007 |
|
RU2443432C2 |
N-MORPHOLINO-N-NITROSOAMINOACETONITRILE AND CYCLODEXTRIN OR CYCLODEXTRIN DERIVATIVE INCLUSION COMPLEXES AND METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF AFFECTING LIVING CELLS WITH NITROGEN OXIDE |
1995 |
- Getsi Joshep
- Vikmon Andrashneh
- Sejtli Jozhef
- Sente Lajosh
- Seman Julianna
|
RU2136698C1 |
VELDORETID, HAVING POOR SOLUBILITY IN PHYSIOLOGICAL CONDITIONS, FOR USE IN TREATING ACROMEGALY, ACROMEGALY WITH MALIGNANT GROWTH, EXPRESSING SST-R5 TUMORS, TYPE 2 DIABETES, HYPERGLYCEMIA AND TUMORS ASSOCIATED WITH HORMONES |
2017 |
|
RU2736590C2 |
BENDAMUSTINE AND CYCLOPOLISACCHARIDE COMPOSITION |
2011 |
- Valery Alakhov
- Grzegorz Pietrzynski
- Kishore Patel
- Tomasz Popek
|
RU2647368C2 |