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2 522 915

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(51)

IPC

A61K31/52(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2012139973/15, 2012-09-19

(24)

Start date

2012-09-19

(22)

Actual filing date

2012-09-19

(45)

Published

2014-07-20

(72)

Inventor

Nilov Dmitrij KonstantinovichShvjadas Vitautas-Juozapas Kajatono

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Universitet Imeni M.V. Lomonosova"

AGENT FOR POLY(ADP-RIBOSO) POLYMERASE INHIBITION Russian patent published in 2014 - IPC A61K31/52 A61P43/00

Abstract RU 2522915 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is an agent for poly(ADP-riboso)polymerase inhibition. The agent represents 7-methylguanine(2-amino-7-methyl-1H-purin-6(7H)-one)- a purine derivative of formula (I) The agent has shown the efficacy higher than that in 7-methyl-xanthine and is non-toxic for the human body.

EFFECT: agent can be used in treating conditions caused by necrotic cell death: stroke, myocardial ischemia, diabetes and complications thereof, shock, neurotrauma, arthritis, colitis, allergic encephalomyelitis and other inflammations.

1 dwg, 2 ex

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RU 2 522 915 C2

Authors

Nilov Dmitrij Konstantinovich

Shvjadas Vitautas-Juozapas Kajatono

Dates

2014-07-20—Published

2012-09-19—Filed