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2 783 240

(13)

(51)

IPC

A61K31/522(2006-01-01)

A61P43/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2022100423, 2022-01-12

(24)

Start date

2022-01-12

(22)

Actual filing date

2022-01-12

(45)

Published

2022-11-10

(72)

Inventor

Nilov Dmitrij KonstantinovichShram Stanislav IvanovichShcherbakova Tatyana AnatolevnaShvyadas Vitautas-Yuozapas Kayatono

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Universitet Imeni M.V.Lomonosova"

USE OF A GUANINE DERIVATIVE TO INHIBIT POLY(ADP-RIBOSE)POLYMERASE Russian patent published in 2022 - IPC A61K31/522 A61P43/00 A61P35/00

Abstract RU 2783240 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to the use of a guanine derivative of formula (I) and its pharmaceutically acceptable salts as inhibitors of human poly(ADP-ribose)polymerase.

EFFECT: effective inhibition of PARP activity, capable of having a cytoprotective effect and suppressing the proliferation of tumor cells.

1 cl, 3 dwg, 2 tbl, 6 ex

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RU 2 783 240 C1

Authors

Nilov Dmitrij Konstantinovich

Shram Stanislav Ivanovich

Shcherbakova Tatyana Anatolevna

Shvyadas Vitautas-Yuozapas Kayatono

Dates

2022-11-10—Published

2022-01-12—Filed