FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to obstetrics and gynaecology, and can be used for the prediction of retardation of intrauterine foetus development. For this purpose a relative content of CD3+CD16+56+-lymphocytes, a level of C3-component of the complement and the soluble receptor of tumour necrosis factor (sTNF-R) are determined in a woman's venous blood at early terms of pregnancy. The prognostic index (PI) is calculated by formula: PI=-0.8911X1-0.0321X2-2.3669X3+11.0779, where X1 is the relative content of CD3+CD16+56+-lymphocytes, %; X2 is the concentration of C3-component of the complement, mg/dl; X3 is the concentration of sTNF-R, ng/ml. If PI<0 retardation of intrauterine foetus growth in the second half of pregnancy is predicted, and if PI>0, a conclusion about a low risk of development of the said pathologic condition is made.
EFFECT: method is low-invasive, makes it possible to identify a risk group by the formation of retardation of intrauterine foetus development from the early terms of gestation, which makes it possible to carry out preventive procedures aimed at the prevention of the said pathological condition.
5 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR EARLY PREDICTION OF FETAL GROWTH RETARDATION | 2019 |
|
RU2718725C1 |
METHOD FOR FETAL GROWTH RESTRICTION PREDICTION | 2020 |
|
RU2738674C1 |
METHOD FOR PREDICTION OF FETAL GROWTH RETARDATION FOR PREGNANT WOMEN WITH PLACENTAL INSUFFICIENCY | 2015 |
|
RU2614692C1 |
METHOD FOR PREDICTING THE RISK OF FETAL GROWTH RETARDATION | 2021 |
|
RU2775435C1 |
METHOD FOR PREDICTING FOETAL GROWTH RETARDATION IN WOMEN WITH HIGH-RISK PREMATURE BIRTH | 2023 |
|
RU2806311C1 |
METHOD FOR PREDICTING FETAL GROWTH RETARDATION IN WOMEN WITH GESTATIONAL DIABETES MELLITUS AND THREATENED LATE MISCARRIAGE | 2022 |
|
RU2792757C1 |
METHOD FOR PREDICTING THE RISK OF FETAL GROWTH RETARDATION, TAKING INTO ACCOUNT EPISTATIC INTERACTIONS OF POLYMORPHIC MENARCHE LOCI | 2021 |
|
RU2775432C1 |
METHOD FOR EARLY PREVENTION OF GESTATIONAL COMPLICATIONS | 2013 |
|
RU2530624C1 |
METHOD IS PROPOSED FOR REVEALING THE HEREDITARY PREDISPOSITION TO THE DEVELOPMENT OF FETAL GROWTH RETARDATION AMONG THE WOMEN SMOKERS | 2017 |
|
RU2646505C1 |
METHOD FOR PREDICTING THE RISK OF FETAL GROWTH RETARDATION SYNDROME IN THE 1ST TRIMESTER | 2021 |
|
RU2775344C1 |
Authors
Dates
2014-08-20—Published
2012-12-21—Filed