DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELL INTO PANCREATIC ENDOCRINE CELL LINE Russian patent published in 2014 - IPC C12N5/71

Abstract RU 2528861 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology. Particularly, the present invention presents a method for providing the higher expression of markers associated with pancreatic endocrine cell line with the use a TGF-beta receptor agonist, such as activin A, activin B, activin C, GDF-8, GDF-11 or GDF-15.

EFFECT: present invention presents methods for stimulating the differentiation of pluripotent stem cells.

7 cl, 4 dwg, 2 ex

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RU 2 528 861 C2

Authors

Rezania Alireza

Dates

2014-09-20—Published

2009-10-22—Filed