ANTIMICROBIAL THERAPEUTIC PREPARATION IN FORM OF FAST-DISSOLVING EFFERVESCENT TABLET Russian patent published in 2014 - IPC A61K31/345 A61K47/02 A61K47/12 A61K9/20 A61J3/10 A61P31/02 

Abstract RU 2533261 C1

FIELD: medicine.

SUBSTANCE: present invention refers to medicine. The preparation contains the active substance furacilin (nitrofural, 2-[(5-nitro-2-furanyl)methylen]hydrazine carboxamide), the excipient - sodium chloride, a gas-forming mixture, an acidity regulator for reducing pH from 6.5 to 7.5 and a lubricant if needed. The gas-forming mixture consists of an organic acid and sodium hydrocarbonate. According to the method for preparing effervescent tablets of furacilin, furacilin and sodium chloride are milled in a combination; all the ingredients are placed into a mixer, and the prepared mixture is tabletted by direct compression. The antimicrobial therapeutic preparation of furacilin in the form of effervescent tablets is used for septic wounds, bed sores, small skin damages, including scratch marks, abrasions, cuts; infectious-inflammatory oral and throat diseases, including acute tonsillitis, stomatitis, gingivitis and tonsillitis. The effervescent tablets of furacilin are storage-stable for two years and water-soluble at room temperature for 5 minutes.

EFFECT: preparing the antimicrobial therapeutic preparation in the form of the effervescent tablets used for preparing the solution for local and external application.

4 cl, 6 tbl, 3 ex

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RU 2 533 261 C1

Authors

Tkachenko Elena Vasil'Evna

Rjabinin Artem Evgen'Evich

Dates

2014-11-20Published

2013-09-18Filed