FIELD: pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry, namely to a composition of a solid dosage form of a sustained-release furacilin preparation for preparing an external and topical solution. Antimicrobial medicinal preparation in the form of tablets with accelerated release contains (wt%): active substance – furacilin (nitrofural) – 2.0–2.5 %; filler – sodium chloride – 87.5–94 %; superdisintegrant with particle size of 110–140 mcm and peroxide content not exceeding 440 ppm – 2–5 %; binder with average molecular weight of 25,000–30,000 – 2–5 %. Superdisintegrant can be crospovidone, and the binding substance can be kollidone.
EFFECT: disclosed is a sustained-release furacilin preparation.
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Authors
Dates
2019-08-06—Published
2019-02-11—Filed