FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biochemistry, particularly to a recombinant human follicle-stimulating hormone (FSH). The above recombinant human FSH contains α2,3- and α2,6-cyalilation, wherein 10% to 90% of the total syalilation represents α2,3-syalilation, and contains cyalic acid in an amount (expressed as a relation of moles of syalic acid to moles of the protein) of 6 mole/mole to 15 mole/mole. What is also declared is a pharmaceutical composition for treating infertility containing the above recombinant human FSH.
EFFECT: invention enables improving pharmacokinetic properties of the recombinant FSH.
12 cl, 13 dwg, 11 ex
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|
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|
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RU2560596C2 |
