FIELD: medicine.
SUBSTANCE: group of inventions refers to infertility treatment. Disclosed is a method of treating infertility in a patient, wherein the infertility treatment involves: (a) identification of said patient as having serum level of antimueller hormone (AMH) less than 15 pmol/l before treatment; (b) identifying said patient as having a variant Ser/Ser at position 680 of a follicle-stimulating hormone receptor (FSH) prior to treatment; and (c) administering a dose of more than 12 to 24 mcg of recombinant follicle-stimulating hormone (FSH) a day or an equivalent dose to said patient. Also disclosed is another version of infertility treatment.
EFFECT: group of inventions provides more effective treatment of infertility in certain patients.
2 cl, 7 dwg, 3 tbl, 9 ex
Title |
Year |
Author |
Number |
COMPOSITION FOR CONTROLLED OVARIAN STIMULATION |
2012 |
|
RU2739037C2 |
COMPOSITION FOR CONTROLLED OVARIAN STIMULATION |
2012 |
|
RU2613324C2 |
PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HCG (HUMAN CHORIONIC GONADOTROPIN HORMONE) |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2724528C2 |
RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) CONTAINING ALPHA-2, 3- AND ALPHA-2, 6-SYALILATION |
2009 |
- Kottingkhem, Ian
- Plaksin, Daniehl'
- Uajt, Richard Bojd
|
RU2537268C2 |
Recombinant follicle-stimulating hormone (FSH), including alpha-2,3 - and alpha-2,6-sialation |
2018 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2745557C1 |
RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) CONTAINING ALPHA-2,3- AND ALPHA-2,6-SYALILATION |
2009 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2682270C2 |
PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HUMAN CHORIONIC GONADOTROPIN |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2588650C2 |
METHODS OF TREATING INFERTILITY |
2016 |
- Arce Saez Joan Carlos
- Ruman Jane
|
RU2723098C2 |
FSH STABILISATION |
2011 |
- Sjogren Heles Ulrika
- Bagger Heidi Louise
|
RU2574012C2 |
RECOMBINANT PROTEIN GBD-SSTAD-SSTAD, A METHOD FOR PRODUCTION AND USE THEREOF |
2019 |
- Lunin Vladimir Glebovich
- Yudin Sergej Mikhajlovich
- Reshetnik Vyacheslav Viktorovich
- Magataev Vali-Magomed Kadievich
|
RU2722849C1 |