FIELD: medicine.
SUBSTANCE: group of inventions refers to reproductive medicine, and aims at treating female infertility. There are provided versions of using a follicle-stimulating hormone (FSH) containing pharmaceutical composition for treating infertility in a patient, having an anti-Müllerian hormone (AMH) serum level of less than 15 pmol/l, as well as not less than 15 pmol/l or not less than 35 pmol/l. Pharmaceutical composition is intended for administration in a dose equal to or equivalent to a certain dose of recombinant human FSH in a day, wherein said recombinant FSH comprises α2,3- and α2,6-sialylation, where from 1 to 50 % of total sialylation is α2,6-sialylation and from 50 to 99 % of total sialylation is α2,3-sialylation.
EFFECT: use of the group of the invention enables higher clinical effectiveness in infertility in the patient.
40 cl, 5 tbl, 11 ex, 8 dwg
Title |
Year |
Author |
Number |
COMPOSITION FOR CONTROLLED OVARIAN STIMULATION |
2012 |
|
RU2613324C2 |
Recombinant follicle-stimulating hormone (FSH), including alpha-2,3 - and alpha-2,6-sialation |
2018 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2745557C1 |
RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) CONTAINING ALPHA-2,3- AND ALPHA-2,6-SYALILATION |
2009 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2682270C2 |
RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) CONTAINING ALPHA-2, 3- AND ALPHA-2, 6-SYALILATION |
2009 |
- Kottingkhem, Ian
- Plaksin, Daniehl'
- Uajt, Richard Bojd
|
RU2537268C2 |
PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HCG (HUMAN CHORIONIC GONADOTROPIN HORMONE) |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2724528C2 |
COMPOSITION FOR TREATING INFERTILITY |
2016 |
- Klein Bjarke Mirner
- Helmgaard Lisbeth
- Arce Saez Joan Carlos
|
RU2704252C2 |
PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HUMAN CHORIONIC GONADOTROPIN |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2588650C2 |
METHOD FOR PREPARING ANTIBODIES HAVING IMPROVED PROPERTIES |
2011 |
- Stedkhim Terrans A.
- Chzha Dunsin
- Lju Limin
|
RU2604811C2 |
LIGANDS TO RECEPTOR OF FOLLICLE-STIMULATING HORMONE (FSH) IN DIAGNOSTICS AND TREATMENT OF TUMORS |
2017 |
- Carpi, Andrea
- Maset, Fabio
- Dal Monte, Renzo
|
RU2755000C2 |
METHODS OF PRODUCING AND USING RECOMBINANT ALPHA-1-ANTITRYPSIN (AAT) AND COMPOSITIONS BASED THEREON |
2020 |
- Vurm, Mariya Zhoao
- Vurm, Florian Mariya
- Yanchauskine, Sabina
- Khamakher, Yurg
- Shtammberger, Uts
|
RU2817416C2 |