COMPOSITION FOR CONTROLLED OVARIAN STIMULATION Russian patent published in 2017 - IPC A61K38/24 A61P5/06 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and is applicable for treating sterility in patient. Follicle-stimulating hormone (FSH) is used in preparing drug for treating sterility in patient. If patient has serum level antimuller hormone (AMH) less than 15 pmol/l, drug contains daily dose equal or equivalent to 11–13 mcg of recombinant FSH (rFSH). Wherein said rFSH includes α2,3- and α2,6-sialylation, where from 1 to 99 % of total sialylation is α2,6-sialylation and from 1 to 99 % of total sialylation is α2,3-sialylation. If patient has serum level of AMH level no less than 15 pmol/l, drug is intended for introduction in daily dose equal or equivalent to 0.09 to 0.19 mcg of human rFSH per kg of patient's body weight. Wherein said rFSH includes α2,3- and α2,6-sialylation, where from 1 to 99 % of total sialylation is α2,6-sialylation and from 1 to 99 % of total sialylation is α2,3-sialylation.

EFFECT: use of group of inventions provides effective treatment of sterility in patient.

10 cl, 8 dwg, 12 tbl, 11 ex