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2 538 612

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IPC

A61K31/404(2006-01-01)

A61P19/10(2006-01-01)

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Application

2013143183/15, 2013-09-23

(24)

Start date

2013-09-23

(22)

Actual filing date

2013-09-23

(45)

Published

2015-01-10

(72)

Inventor

Gudyrev Oleg SergeevichRemizov Pavel PavlovichSobolev Mikhail SergeevichFajtel'Son Aleksandr VladimirovichPokrovskij Mikhail VladimirovichRadzhkumar Densing Samuehl RadzhPokrovskaja Tat'Jana Grigor'EvnaKorokin Mikhail ViktorovichKochkarov Vladimir IskhakovichArustamova Anna Aleksandrovna

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Natsional'Nyj Issledovatel'Skij Universitet"

METHOD FOR ROSUVASTATIN CORRECTION OF BONE MICROCIRCULATION IN EXPERIMENTAL OSTEOPOROSIS AND ACCOMPANYING FRACTURES Russian patent published in 2015 - IPC A61K31/404 A61P19/10

Abstract RU 2538612 C1

FIELD: medicine.

SUBSTANCE: method involves simulating osteoporosis in Wistar female rats by a bilateral ovariectomy and osteoporotic changes and pharmacological correction of pathological conditions with rosuvastatin 0.86 mg/kg intragastrically daily in a single dose once a day.

EFFECT: using the method enables increasing the bone blood supply that promotes delaying osteoporosis and creating the favourable environment for the fracture union.

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RU 2 538 612 C1

Authors

Gudyrev Oleg Sergeevich

Remizov Pavel Pavlovich

Sobolev Mikhail Sergeevich

Fajtel'Son Aleksandr Vladimirovich

Pokrovskij Mikhail Vladimirovich

Radzhkumar Densing Samuehl Radzh

Pokrovskaja Tat'Jana Grigor'Evna

Korokin Mikhail Viktorovich

Kochkarov Vladimir Iskhakovich

Arustamova Anna Aleksandrovna

Dates

2015-01-10—Published

2013-09-23—Filed