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2 832 054

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IPC

A61B17/00(2006-01-01)

A61K31/726(2006-01-01)

A61P43/00(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2024113777, 2024-05-21

(24)

Start date

2024-05-21

(22)

Actual filing date

2024-05-21

(45)

Published

2024-12-18

(72)

Inventor

Radzhkumar Densing Samuel RadzhChebotarev Stanislav NikolaevichFaitelson Aleksandr VladimirovichArtiushkova Elena BorisovnaIvanov Aleksandr ViktorovichPavlov Viktor Konstantinovich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennyi Meditsinskii Universitet" Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

METHOD FOR PHARMACOLOGICAL CORRECTION OF OXIDATIVE DISORDERS ACCOMPANYING OSTEOPOROSIS IN EXPERIMENT WITH CHONDROITIN SULPHATE Russian patent published in 2024 - IPC A61B17/00 A61K31/726 A61P43/00 G09B23/28

Abstract RU 2832054 C1

FIELD: experimental medicine.

SUBSTANCE: invention refers to experimental medicine, namely pharmacology and traumatology. Bilateral ovariectomy is performed in female Wistar rats. On the next postoperative day, chondroitin sulphate 68.6 mg/kg is administered once a day intragastrically for 8 weeks. On 57th day of the experiment, osteoporotic fractures of the hip and shoulder are simulated, and the introduction of chondroitin sulphate in the specified dose is continued until 12 weeks after the beginning of the experiment.

EFFECT: due to antioxidant properties of the preparation, the method enables to slow down the development of osteoporotic disorders in hypoestrogenic conditions, which in turn creates favourable conditions for successful fracture consolidation.

1 cl, 1 ex

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RU 2 832 054 C1

Authors

Radzhkumar Densing Samuel Radzh

Chebotarev Stanislav Nikolaevich

Faitelson Aleksandr Vladimirovich

Artiushkova Elena Borisovna

Ivanov Aleksandr Viktorovich

Pavlov Viktor Konstantinovich

Dates

2024-12-18—Published

2024-05-21—Filed