FIELD: biotechnology.
SUBSTANCE: synthetic DNA is proposed, encoding human erythropoietin, having the sequence Seq ID No. 1, comprising its expression vector, the method of production of erythropoietin producer strain, and a strain of a Chinese hamster ovary cells - producer of recombinant human erythropoietin, deposited under the number RKKK(P) 761 D.
EFFECT: invention enables to increase the expression level of recombinant human erythropoietin.
5 cl, 1 tbl, 8 dwg, 4 ex
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| STRAIN OF CHINESE HAMSTER OVARY CELLS CHO-EPO 4A9 - PRODUCER OF HIGHLY SIALYLATED ERYTHROPOETHIN | 2016 |
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| STRAIN CHO OF THE CULTURED CHINESE HAMSTER CELLS - A PRODUCER OF HUMAN ERYTHROPOIETIN | 1995 |
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| METHOD OF PREPARING HUMAN RECOMBINANT ERYTHROPOIETIN, STRAIN OF CULTURED CHINESE HAMSTER OVARIAN CELLS - A PRODUCER OF ERYTHROPOIETIN | 1998 |
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| STRAIN OF CELLS OF CHINESE HAMSTER OVARIES - PRODUCER OF RECOMBINANT ANTIBODY AGAINST TUMOUR NECROSIS FACTOR ALPHA OF HUMAN BEING | 2014 |
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| CULTURE CELL STRAIN CHO-IL7/13 PRODUCING HUMAN INTERLEUKIN-7 | 2012 |
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| CHO-SE-9/4 CELL STRAIN, PRODUCER OF CHIMERIC HUMAN ERYTHROPOIETIN ANTIBODY AND CHIMERIC ANTIBODY PRODUCED BY SAID STRAIN | 2019 |
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| STRAIN OF CULTIVATED CELLS OF CHINA HAMSTER - PRODUCER OF ERYTHROPOETYN OF MAN | 0 |
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SU1555359A1 |
