FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to a method of automated morphometric myelofibrosis diagnostics. The method essence consists in the fact that overview images of zones with different optical properties with determinable fibrous and heamopoietic properties of a biological tissue are performed. Ratios of areas of the said zones of at least three paraffin cuts of trepanobiopsy samples are calculated. The coefficient (Cop) is calculated as the ratio of the fibrous tissue area to the area of the heamopoietic tissue by formula. If the value Cop ≥14.5%, myelofibrosis is diagnosed.
EFFECT: application of the claimed method makes it possible to increase the accuracy and improve the efficiency of myelofibrosis diagnostics.
7 cl, 1 tbl, 4 dwg, 1 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF DETERMINING LYSOSOMAL CATIONIC PROTEINS IN TISSUE GRANULOCYTES | 1999 |
|
RU2168938C2 |
METHOD OF DETERMINING THE SYNTHETIC ACTIVITY OF POLYCHROMATOPHILIC ERYTHROBLASTS AND ERYTHROCYTES OF BIRDS | 2023 |
|
RU2799424C1 |
DIAGNOSTIC TECHNIQUE FOR ENDOGENOUS INTOXICATION | 2010 |
|
RU2456596C2 |
METHOD OF FINDING GRANULOSE IN HISTOLOGICAL PREPARATIONS OF SCLERO-CYSTIC OVARIES OF WOMAN | 1991 |
|
RU2031407C1 |
METHOD OF POSTNATAL DIAGNOSTICS OF FOETAL ALCOHOL SYNDROME IN DECEASED YOUNG CHILDREN | 2013 |
|
RU2547568C1 |
EARLY DIAGNOSTIC TECHNIQUE FOR CHRONIC DUST BRONCHITIS | 2014 |
|
RU2572724C1 |
METHOD FOR PREDICTION OF RISK OF VESICOURETHRAL ANASTOMOSIS STENOSIS DEVELOPMENT AFTER RADICAL PROSTATECTOMY | 2016 |
|
RU2631606C1 |
PATHOMORPHOLOGICAL DIAGNOSTIC TECHNIQUE FOR BIFURCATION FAILURE OF VESSELS OF CEREBRAL ARTERIAL CIRCLE | 2014 |
|
RU2575588C1 |
METHOD OF DEFINING COMPARATIVE COLLAGEN FIBRE AREA IN HISTOLOGICAL PREPARATION | 2006 |
|
RU2332665C1 |
METHOD OF DETECTING PRESENCE OF SYSTEMIC REACTION OF CONNECTIVE TISSUE, CONDITIONED BY DEVELOPMENT OF SYNDROME OF COMBINED DYSTROPHIC-DEGENERATIVE CHANGES OF MESENCHYMAL DERIVATIVES IN CASE OF LOCAL CHRONIC INFLAMMATORY PROCESS | 2012 |
|
RU2493777C1 |
Authors
Dates
2015-06-10—Published
2013-11-01—Filed