VERSIONS OF PLASMINOGEN AND PLASMIN Russian patent published in 2015 - IPC C07K14/47 C12N9/68 C12N15/11 A61K38/17 

Abstract RU 2564131 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of biotechnology, namely to obtaining versions of plasminogen and plasmin, containing one or several point mutations in catalytic domain, which reduce or prevent autocatalytic loss of plasmin protease activity, and can be used in medicine.

EFFECT: invention makes it possible to obtain autoproteolytically stable plasmin.

51 cl, 10 dwg, 3 tbl, 5 ex

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RU 2 564 131 C2

Authors

Zwaal, Richard Reinier

Dates

2015-09-27Published

2010-07-09Filed