FIELD: chemistry.
SUBSTANCE: group of inventions relates to devices and methods for analysis using specific binding and is intended for determining the presence or amount of an analyte in a sample. The immunochromatographic device comprises a membrane carrying a capture antibody bound thereto in a test zone, and a structure having conjugates, fluidly coupled to the membrane at a proximal end. The structure comprises a detector antibody having a reporter moiety conjugated therewith. Each of said capture and detector antibodies is a monoclonal antibody produced by hybridoma cells deposited under access number DSM ACC3092 (monoclonal antibody LG96) or DSM ACC3093 (monoclonal antibody MG97). The analyte is a Z-AAT protein, present in the sample from a PiZ gene carrier.
EFFECT: use of the group of inventions improves the efficiency of determining presence of an analyte, particularly a Z-AAT protein.
25 cl, 33 dwg, 1 tbl, 5 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR MARKER DETECTION IN SMALL AMOUNT OF BIOLOGICAL FLUID SAMPLE | 2011 |
|
RU2575559C2 |
TEST STRIP FOR HIGHLY SENSITIVE IMMUNOCHROMATOGRAPHIC ANALYSIS | 2013 |
|
RU2523393C1 |
ANALYSIS FOR GLYCATED PROTEINS | 2015 |
|
RU2698311C2 |
APPARATUS FOR DETECTING ANTIGENS AND USE THEREOF | 2010 |
|
RU2574991C2 |
ANTIBODIES FOR LABORATORY DIAGNOSTICS OF THE CONCENTRATION OF INTERLEUKIN-11 | 2020 |
|
RU2763178C2 |
TEST SYSTEM FOR IMMUNOCHROMATOGRAPHIC ASSAY OF CARDIAC PROTEIN BINDING FATTY ACIDS AND TROPONIN I IN WHOLE BLOOD SAMPLE FOR INSTANT DIAGNOSING OF MYOCARDIAL INFARCTION (VERSIONS) | 2010 |
|
RU2464572C1 |
METHOD OF IMMUNOCHROMATOGRAPHIC DETERMINATION OF SPECIFIC ANTIBODIES | 2013 |
|
RU2545909C2 |
DEVICE AND METHOD OF SIMULTANEOUS DEFINITION OF BLOOD TYPE, SEROLOGICAL CROSS-CHECK AND ANTIBODY ANALYSIS | 2004 |
|
RU2358267C2 |
NEW CANCER ANTIGEN FOR EARLY DETECTION OF CANCER, METHOD FOR OBTAINING, ISOLATION AND DETECTION THEREOF | 2020 |
|
RU2818471C2 |
METHOD FOR MULTI-ANALYTE IMMUNOASSAY | 2014 |
|
RU2593787C2 |
Authors
Dates
2015-11-20—Published
2011-09-23—Filed