METHOD OF PRODUCING 2-BROMO-4,5-DIALKOXYBENZOIC ACID Russian patent published in 2016 - IPC C07C51/363 C07C51/367 C07C65/21 B01J23/72 B01J31/02 

FIELD: chemistry.

SUBSTANCE: method of producing 2-bromo-4,5-dialkoxybenzoic acid represented by the following formula , where each of R¹ and R² is a lower alkyl group, includes reacting 3,4-dialkoxybenzoic acid, represented by the following formula , where R¹ and R² have the same values as defined above, with bromine in a concentrated hydrochloric acid, where the reaction is carried out at 10-45°C. The method of producing 4,5-dialkoxy-2-hydrobenzoic acid, represented by the following formula , where each of R¹ and R² is a lower alkyl group, includes reacting 3,4-dialkoxybenzoic acid, represented by the following formula (1), where R¹ and R² have the same values as defined above, with bromine in a concentrated hydrochloric acid, where the reaction is carried out at 10-45°C; and the hydrolysis of the obtained 2-bromo-4,5-dialkoxybenzoic acid, represented by the following formula (2), where R¹ and R² have the same values as defined above, in the presence of a copper compound or an amine compound.

EFFECT: high efficiency.

11 cl, 3 tbl, 3 ex