FIELD: medicine.
SUBSTANCE: present invention relates to novel aromatic butan-2-ol compounds of formula I, methods for preparation thereof, a pharmaceutical composition and use to obtain a medicament for treating and/or preventing a disease or disorder caused by tubercle bacillus infection. A compound of formula I of the present invention has advantages in the treatment and/or prevention of a disease or disorder caused by tubercle bacillus infection. In the compound of formula I: 
R1 is hydrogen, fluorine, chlorine, bromine, iodine or methoxy; R2 is hydrogen, fluorine, chlorine, bromine or iodine; R3 is hydrogen, fluorine, chlorine, bromine, iodine or C1-8-alkyl, inserted in the o-, m- or p-position of the phenyl ring; R4 is phenyl, substituted phenyl or naphthyl and R5 is hydroxy or methoxy.
EFFECT: prevention of a disease or disorder caused by tubercle bacillus infection.
11 cl, 3 tbl, 46 ex
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