FIELD: medicine.
SUBSTANCE: actuating the reaction of the cardiomyocytes taken from induced pluripotent stem cells and a specified medicinal product in a high-efficiency analysis system, measuring resistance or using a multielectrode matrix are followed by detecting a variation in the beat frequency and calculating a portion of abnormal heart rhythms (AHR); the AHR of 0.2 or less is the indicator of the low risk of arrhythmia.
EFFECT: higher accuracy.
23 cl, 2 tbl, 1 ex
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| DEVICE, CONTAINING CARDIOMYOCYTES, AND METHOD OF PRODUCTION AND APPLICATION THEREOF | 2010 |
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RU2524134C2 |
| EVALUATION METHOD OF MORPHOFUNCTIONAL STATE OF INDUCED PLURIPOTENT STEM CELLS OF PARKINSONIAN PATIENTS, WHICH ARE DIFFERENTIATED TO DOPAMINERGIC NEURONS | 2012 |
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RU2501853C1 |
| 3-PHENYL-3,7-DIAZABICYCLO[3,3,1]NONANE COMPOUNDS, METHOD FOR THEIR PREPARING AND MEDICINAL AGENTS CONTAINING THESE COMPOUNDS | 2002 |
|
RU2299210C2 |
| METHOD OF INDUCTION OF PLURIPOTENT STEM CELLS DIFFERENTIATION INTO CARDIOMYOCYTES | 2007 |
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RU2433174C2 |
| METHODS FOR TREATMENT OF HEART FAILURE AND ISCHEMIC-REPERFUSION INJURY OF HEART | 2017 |
|
RU2767445C2 |
| SUCCINIC ACID ESTER 5-HYDROXYADAMANTAN-2-ONE, WHICH PREVENTS THE DEVELOPMENT OF CARDIAC ARRHYTHMIAS | 2020 |
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RU2757477C1 |
| METHOD OF PROVIDING SAFETY OF APPLICATION OF PLURIPOTENT STEM CELLS IN TISSUE-SUBSTITUTING THERAPY BY MEANS OF ARTIFICIAL CHROMOSOMES | 2012 |
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RU2548819C2 |
| REMOVING UNDIFFERENTIATED STEM CELLS AGENT AND UNDIFFERENTIATED STEM CELL REMOVAL METHOD | 2017 |
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RU2735247C1 |
| METHOD OF TREATING CARDIOVASCULAR DISEASE | 2023 |
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RU2822010C1 |
| METHOD OF STEM CELLS DIFFERENTIATION INTO MIOCARDIAL CELLS INDUCTION | 2004 |
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RU2392315C2 |
