USE OF INDUCED PLURIPOTENT HUMAN STEM CELLS FOR ASSESSING CITO- AND EMBRYOTOXIC PROPERTIES OF PHARMACOLOGICAL COMPOUNDS Russian patent published in 2016 - IPC A61K35/545 G01N33/48 

Abstract RU 2599847 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to biotechnology and pharmacology, and can be used for assessing cito- and embryotoxic properties of pharmaceutical compounds. For this reason use induced pluripotent stem cells produced by reprogramming of human skin fibroblasts.

EFFECT: using the given method enables evaluation of the availability of cito- and embryotoxic properties, compounds representing pharmacological interest.

1 cl, 4 ex, 3 dwg

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RU 2 599 847 C1

Authors

Novosadova Ekaterina Vyacheslavovna

Andreeva Lyudmila Aleksandrovna

Arseneva Elena Lvovna

Grivennikov Igor Anatolevich

Illarioshkin Sergej Nikolaevich

Lebedeva Olga Sergeevna

Makarova Irina Vladimirovna

Manuilova Ekaterina Semenovna

Myasoedov Nikolaj Fedorovich

Tarantul Vyacheslav Zalmanovich

Dates

2016-10-20Published

2015-09-10Filed