FIELD: biotechnology.
SUBSTANCE: group of inventions relates to biotechnology and represents versions of methods of creating a set of adjacent fragments of the analyzed genome region. Method includes fragmenting of crosswise cross-linked DNA, ligation of fragmented crosswise cross-linked DNA, cross-linking reversion, determination of at least part of sequences of ligated DNA fragments, including nucleotide target-sequence, and use of certain sequences to create a set of adjacent fragments of the analyzed region of genome.
EFFECT: using given methods enables to obtain contigs and detect mutations in one region of genome, but spaced apart over long distances.
18 cl, 3 dwg, 2 tbl, 1 ex
| Title |
Year |
Author |
Number |
| CO-LOCALISED CHROMATIN TRAPPING AND CHARACTERISING |
2006 |
- De Lat Vauter
- Grosveld Frank
|
RU2478716C2 |
| METHOD AND PRODUCT FOR LOCALISED OR SPATIAL DETECTION OF NUCLEIC ACID IN TISSUE SAMPLE |
2012 |
- Frisen Jonas
- Stokhl Patrik
- Lundeberg Joakim
|
RU2603074C2 |
| SPATIAL MAPPING OF MOLECULAR PROFILES OF BIOLOGICAL TISSUE SAMPLES |
2016 |
- Pierik, Anke
- Wimberger-Friedl, Reinhold
- Van Driel, Marc
|
RU2733545C2 |
| DIRECT CAPTURE, AMPLIFICATION AND SEQUENCING OF TARGET DNA USING IMMOBILISED PRIMERS |
2011 |
- Mjulljukangas Samuehl'
- Buenrostro Dzhejson
- Dzhi Khehnli P.
|
RU2565550C2 |
| NUCLEOTIDE SEQUENCE OF CLASSIC SWINE FEVER VIRUS (CSFV) (VARIANTS), POLYPEPTIDE CSFV, PESTOVIRAL VACCINE AGAINST CSFV, DIAGNOSTIC SET AND METHOD |
1995 |
- Mormann Robertus Jakobus Marija
- Van Rejn Petrus Antonius
|
RU2201451C2 |
| METHODS OF OBTAINING LIBRARIES OF TWO-CHAIN DNA AND METHODS OF SEQUENCING FOR IDENTIFYING METHYLATED CYTOSINES |
2015 |
- Kol Mulet Lorens
- Pejnado Morales Migel A.
|
RU2688485C2 |
| HIGH THROUGH-PUT ANALYSIS OF TRANSGENE BORDERS |
2012 |
- Tsao Tszekhuej
- Novak Stefen
- Chzhou Nin
|
RU2603265C2 |
| GENOMIC SELECTION AND SEQUENCING USING CODED MICROCARRIERS |
2010 |
- Van De Stolpe Anya
- Den Tonder Yakob M.J.
- Van Der Zag Piter J.
|
RU2609630C2 |
| SET OF PROBES FOR ANALYZING DNA SAMPLES AND METHODS FOR THEIR USE |
2016 |
- Dahl, Carl Oscar Fredrik
- Ericsson, Olof John
- Karlsson, Filip
- Roos, Fredrik
|
RU2753883C2 |
| GENOME-WIDE LIBRARIES OF INDIVIDUAL CELLS FOR BISULFITE SEQUENCING |
2018 |
- Adey, Andrew C.
- Mulqueen, Ryan
- Steemers, Frank J.
- Pokholok, Dmitry K.
- Norberg, Steven
|
RU2770879C2 |
