DOWN REGULATION OF TRANSCRIPTION OF SINE/ALU RETROTRANSPOSONS FOR INDUCING OR RECOVERY OF PROLIFERATION AND/OR PLURIPOTENCY OF STEM CELL Russian patent published in 2016 - IPC C12N5/00

Abstract RU 2603731 C2

FIELD: biotechnologies.

SUBSTANCE: invention relates to biotechnology. Method involves reduction of level or activity of transcripts of SINE/Alu retrotransposons in cell in amount sufficient for inducing or recovery of proliferation ability and/or pluripotency of specified mammal cell.

EFFECT: method of inducing and/or recovery and/or maintenance of phenotype without signs of aging or its aspects is described, in particular ability of proliferation and/or pluripotency in mammal cell.

25 cl, 58 dwg, 9 tbl, 3 ex

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RU 2 603 731 C2

Authors

Lunjak Viktorija V.

Dates

2016-11-27—Published

2011-10-20—Filed