FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Method of producing L-lysine using recombinant coryneform microorganism able to produce L-lysine is disclosed, where recombinant coryneform microorganism is transformed by means of insertion of acetate-inducible promoter below stop codon of target gene on chromosome for attenuation of target gene expression and enhancing of ability of recombinant coryneform microorganism to produce L-lysine, where target gene is gene located in nodal point of L-lysine biosynthesis path.
EFFECT: invention increases production of L-lysine in comparison with parent strain of microorganism.
4 cl, 2 dwg, 12 tbl, 13 ex
Authors
Dates
2017-03-24—Published
2014-10-08—Filed