FIELD: biotechnology.
SUBSTANCE: disclosed is a version of pyruvate dehydrogenase containing at least one amino acid substitution in amino acids in positions 190–205 or in amino acids in positions 415–440 of SEQ ID NO: 1. Disclosed is a polynucleotide encoding said variant of pyruvate dehydrogenase. Disclosed is a microorganism of the genus Corynebacterium, which produces an L-amino acid containing said version of pyruvate dehydrogenase. Disclosed is a method of producing L-amino acid using said microorganism of the genus Corynebacterium.
EFFECT: group of inventions makes it possible to increase ability to produce L-amino acid in modified strain as compared to control strain.
10 cl, 11 tbl, 14 ex
| Title |
Year |
Author |
Number |
| MICROORGANISM WITH IMPROVED ABILITY TO PRODUCE L-LYSINE AND METHOD OF OBTAINING L-LYSINE USING THIS MICROORGANISM |
2015 |
- Huh Lan
- Lee Kwang Ho
- Kim Hyung Joon
- Moon Jun Ok
- Ryu Song-Gi
|
RU2668176C1 |
| METHOD OF PRODUCING L-AMINO ACIDS |
2014 |
- Moon Dzun Ok
- Lim Sang Dzo
- Kvon Do Khiun
- Li Kvang Kho
- Bae Khiun Von
|
RU2614258C2 |
| METHOD OF PRODUCING L-AMINO ACIDS |
2014 |
- Moon Dzun Ok
- Lim Sang Dzo
- Kvon Do Khiun
- Li Kvang Kho
- Bae Khiun Von
|
RU2651461C2 |
| METHOD OF PRODUCING L-AMINO ACIDS |
2018 |
- Moon, Jun Ok
- Lim, Sang Jo
- Kwon, Do Hyun
- Lee, Kwang Ho
- Bae, Hyun Won
|
RU2697005C2 |
| MICROORGANISM OF CORYNEBACTERIUM GENUS THAT PRODUCES L-AMINO ACIDS, AND METHOD FOR OBTAINING L-AMINO ACIDS USING THIS MICROORGANISM |
2019 |
- Son Syn-Chzhu
- Yun Ben Khun
- Li Kvan U
- Kim Son Khe
- Ben Khe Chzhon
- Chan Dzhin Suk
- Kim Khen Dzhun
- Sin En Uk
|
RU2754781C1 |
| MICROORGANISM OF CORYNEBACTERIUM SPECIES HAVING ENHANCED L-LYSINE PRODUCIBILITY AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Park Sang Hee
- Moon Jun Ok
- Bae Hyun Won
- Lee Kwang Ho
|
RU2667425C2 |
| Corynebacterium MICROORGANISMS, CAPABLE OF RECYCLING XYLOSE, AND METHOD OF PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2013 |
- Ra So Jon
- Khu Lan
- Kim Chan Gem
- Li Kvan Kho
- Mun Dzhun Ok
- Li Kjun Khan
- Sun Dzhin Sok
- Kim Khjung Chun
|
RU2584593C2 |
| MICROORGANISM HAVING IMPROVED L-LYSINE PRODUCING ABILITY AND METHOD FOR PRODUCING L-LYSINE BY USING SAID MICROORGANISM |
2015 |
- Lee, Peter
- Moon, Jun Ok
- Kim, Hyung Joon
- Ryu, Song Gi
|
RU2663135C2 |
| CORYNEBACTERIUM GENUS MICROORGANISM WITH IMPROVED ABILITY TO PRODUCE L-LYSINE AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Moon Jun Ok
- Park Sang Hee
- Huh Lan
- Lee Kwang Ho
|
RU2651505C1 |
| MICROORGANISMS OF CORYNEBACTERIUM SP., CAPABLE OF PRODUCING L-LYSINE, AND A METHOD FOR PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2016 |
- Lee, Seung Bin
- Chung, Yoon Hee
- Kim, Hyung Joon
- Kang, Doo Jin
- Bang, Seong Eun
- Ryu, Song Gi
|
RU2687206C1 |
