FIELD: medicine.
SUBSTANCE: method involves fine-needle aspiration biopsy of thyroid nodules under the control of ultrasound, at that, the puncture needle with the aspirate contained therein is washed twice in a preservative NovaPrep solution, centrifuged, supernatants are selected, immunocytochemical analysis of Ki-67 expression is performed, and the diagnostic indicator is calculated by the formula 
where HS=∑P(i)×i, i is the intensity of staining, expressed as scores (0 to 3), P(i) is the percentage of cells stained with different intensities and at p>0.5 formation is considered malignant, at p<0.5 it is considered benign.
EFFECT: improved method accuracy and informativity.
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