FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for diagnosing malignant neoplasms of the thyroid gland. Fine-needle aspiration biopsy for cytological examination is performed in the patients under the control of ultrasonic scanning. If observing an uncertain result, total microRNA is recovered from the remaining aspirate and expression of miRNA-146b and miRNA-574-3p is determined. Obtained values are substituted into the formula for calculating the diagnostic coefficient K. If the K value is equal to or more than 0.54, a malignant neoplasm of the thyroid gland is diagnosed.
EFFECT: method enables more accurate diagnosis of thyroid malignancies by determining expression of miRNA-146b and miRNA-574-3p.
1 cl, 1 dwg, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF RISK OF RECURRENT THYROID CANCER AFTER RADICAL SURGERY | 2024 |
|
RU2822578C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF NODULAR FORMATIONS OF THE HUMAN THYROID GLAND | 2021 |
|
RU2757347C1 |
| METHOD FOR PREDICTION OF RECURRENT THYROID CANCER AFTER RADICAL SURGERY | 2024 |
|
RU2823255C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF THYROID NEOPLASMS | 2019 |
|
RU2705110C1 |
| METHOD FOR COMPLEX PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGNANT NODULES OF THE THYROID GLAND | 2022 |
|
RU2805941C1 |
| METHOD FOR PREOPERATIVE DIAGNOSIS OF MEDULLARY THYROID CANCER | 2023 |
|
RU2819521C1 |
| METHOD FOR PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF ANAPLASTIC THYROID CANCER | 2021 |
|
RU2759128C1 |
| METHOD FOR PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGNANT NODULAR FORMATIONS OF THE THYROID GLAND | 2021 |
|
RU2783304C1 |
| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR INDIVIDUAL'S THYROID NEW GROWTHS | 2014 |
|
RU2569154C1 |
| METHOD OF DETERMINING RISK OF DEVELOPING PAPILLARY THYROID CANCER | 2023 |
|
RU2807880C1 |
