FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for preoperative diagnosis of medullary thyroid cancer (MTC). MicroRNA is recovered from thyroid tumour samples obtained by fine-needle aspiration puncture biopsy. Expression levels of microRNA-375 and microRNA-323 are determined. Calculating value of 1/[(expression level of microRNA-375) × (expression level of microRNA-323)]. If this value is equal to or less than 110, MTC is diagnosed.
EFFECT: method provides simplification and acceleration of preoperative diagnosis of MTC while maintaining high accuracy of analysis by using a minimum set of significant microRNAs.
1 cl, 2 tbl, 2 ex
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