METHOD FOR LOCAL-DISTRIBUTED COLON CANCER METASTASIS Russian patent published in 2017 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: immunophenotyping of blood lymphocytes taken from the ulnar vein prior to surgery, as well as lymphocytes of the tumor tissue and the peritumoral region is performed to identify subpopulations of lymphocytes, such as αβ_Cr - T-lymphocytes with a receptor αβ in the blood (X1), CD4+_Peri - T-helper-inductor lymphocytes in the peritumoral zone (X2), CD8+_Peri - cytotoxic T-lymphocytes in the peritumoral zone (X3), CD19+_Peri - B-lymphocytes in the peritumoral zone (X4), CD19+_tum - B-lymphocytes in the tumor zone (X5), then the risk of metastasis of locally advanced colon cancer R_m is determined by the formula and with R_m value of 0.5 or more, metastases of locally advanced colon cancer are predicted for the next 2 years, with R_m value of less than 0.5, no risk is predicted.

EFFECT: method allows to timely and individually predict the development of metastases of locally advanced colon cancer in the next 2 years.

2 ex, 2 tbl