TREATMENT OF DISEASES ASSOCIATED WITH METHIONINE SULFOXIDE REDUCTASE A (MSRA), BY MSRA NATURAL ANTISENSE TRANSCRIPT INHIBITION Russian patent published in 2017 - IPC C12N15/13 

Abstract RU 2620978 C2

FIELD: biotechnology.

SUBSTANCE: oligonucleotides are described that modulate methionine sulfoxide reductase A (MSRA) expression, in particular, by targeting the interaction with the natural antisense methionine sulfoxide reductase A (MSRA) polynucleotides. This invention also relates to application of the said oligonucleotides for treatment of diseases and disorders associated with methionine sulfoxide reductase A (MSRA) expression.

EFFECT: invention expands the arsenal of tools for treatment of diseases and disorders associated with methionine sulfoxide reductase A (MSRA) expression.

28 cl, 2 dwg, 2 ex, 1 tbl

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RU 2 620 978 C2

Authors

Kollard Dzhozef

Khorkova Sherman Olga

Dates

2017-05-30Published

2011-05-25Filed