TREATMENT OF DISEASES ASSOCIATED WITH METHIONINE SULFOXIDE REDUCTASE A (MSRA), BY MSRA NATURAL ANTISENSE TRANSCRIPT INHIBITION Russian patent published in 2017 - IPC C12N15/13

Abstract RU 2620978 C2

FIELD: biotechnology.

SUBSTANCE: oligonucleotides are described that modulate methionine sulfoxide reductase A (MSRA) expression, in particular, by targeting the interaction with the natural antisense methionine sulfoxide reductase A (MSRA) polynucleotides. This invention also relates to application of the said oligonucleotides for treatment of diseases and disorders associated with methionine sulfoxide reductase A (MSRA) expression.

EFFECT: invention expands the arsenal of tools for treatment of diseases and disorders associated with methionine sulfoxide reductase A (MSRA) expression.

28 cl, 2 dwg, 2 ex, 1 tbl

Similar patents RU2620978C2

Title	Year	Author	Number
TREATMENT OF INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 (IFRD1) ASSOCIATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IFRD1	2011	Kollard Dzhozef Khorkova Sherman Olga Kojto Karlos	RU2611195C2
TREATMENT OF DISEASES ASSOCIATED WITH THE SIALIDASE 4 (NEU4) GENE, BY GENE NEU4 NATURAL ANTISENSE TRANSCRIPT INHIBITION	2011	Kollard Dzhozef Khorkova Sherman Olga	RU2624048C2
TREATMENT OF ALPHA-L-IDURONIDASE (IDUA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IDUA	2011	Kollard Dzhozef Khorkova Sherman Olga Kojto Karlos Gang Shen	RU2597972C2
TREATMENT OF DISEASES ASSOCIATED WITH ATONAL HOMOLOG 1 (ATON1) BY INHIBITING NATURAL ANTISENSE TRANSCRIPT OF GENE ATON1	2011	Kollard Dzhozef Khorkova Sherman Olga	RU2585229C2
TREATMENT OF DISEASES RELATED WITH GENE DLG BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT OF DLG GENE	2011	Kollard Dzhozef Khorkova Sherman Olga Kojto Karlos	RU2611190C2
TREATMENT OF DISEASES ASSOCIATED WITH FRATAXIN (FXN), BY INHIBITING NATURAL ANTISENSE FXN TRANSCRIPT	2012	Kollard Dzhozef Khorkova Sherman Olga	RU2620980C2
TREATING DISEASES, ASSOCIATED WITH NANOG, BY INHIBITION OF NATURAL ANTISENSE NANOG TRANSCRIPT	2011	Kollard Dzhozef Khorkova Sherman Olga	RU2608493C2
TREATMENT OF DISEASES, ASSOCIATED WITH PROTEIN OF PROSTATE APOPTOTIC RESPONSE PAR4, BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT OF PAR4 GENE	2011	Kollard Dzhozef Khorkova Sherman Ol'Ga	RU2575608C2
TREATMENT OF SODIUM CHANNEL, VOLTAGE-GATED, ALPHA SUBUNIT (SCNA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SCNA	2011	Kollard Dzhozef Khorkova Sherman Olga De Leon Belinda Kojto Karlos Khsyao Dzhejn Kh., Dr.	RU2588654C2
TREATMENT OF TUMORS OF DISEASES RELATED TO THE GENOM-SUPPRESSOR BY THERAPY OF NATURAL TRANSCRIPT INHIBITION IN ANTI-SIGNIFICANT ORIENTATION REGARDING THIS GENE	2009	Kollard Dzhozef Khorkova Sherman Olga	RU2618688C2

RU 2 620 978 C2

Authors

Kollard Dzhozef

Khorkova Sherman Olga

Dates

2017-05-30—Published

2011-05-25—Filed