METHOD FOR CARDIOPLEGIA Russian patent published in 2017 - IPC A61K31/47 A61K31/65 A61K31/133 A61K33/14 A61K33/08 A61K47/04 A61P43/00 

Abstract RU 2635523 C2

FIELD: medicine.

SUBSTANCE: to stop the heart and maintain it in a stopped state, a cardioplegic solution is used which is obtained from the following components: potassium chloride - 7.45 g; magnesium sulfate - 2.34 g; trometamol - 0.5 g; mannitol - 35.9 g; distilled water - up to 1000 ml, with introduction of 1 M hydrochloric acid until a pH of 7.6-8.0, which is mixed with blood from the oxygenator in a ratio of 1:1 to 1:4 and injected into the heart at a rate of 100-300 ml/min using at least 400 ml of solution; and to maintain the asystole, a cardioplegic solution is used which is obtained from the following components: potassium chloride - 2.125 g; magnesium sulfate - 2.34 g; trometamol - 0.5 g; mannitol - 58.28 g; distilled water - up to 1000 ml, with introduction of 1 M hydrochloric acid until a pH of 7.6-8.0, which is mixed with blood from the oxygenator in a ratio of 1:4 and injected into the heart at a rate of 100-150 ml/min.

EFFECT: improved safety of cardioplegia using different cardioplegic solutions.

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RU 2 635 523 C2

Authors

Volgushev Valentin Evgenevich

Andronov Sergej Petrovich

Merkin Nikolaj Aleksandrovich

Dates

2017-11-13Published

2016-04-29Filed