METHOD AND SYSTEM FOR CELLULAR ANALYSIS BY MASS CYTOMETRY Russian patent published in 2017 - IPC C12M1/34 G01N15/10 G01N33/569 G01N33/483 

FIELD: biotechnology.

SUBSTANCE: method and system for cell analysis are proposed. The method comprises provision of a group of labeled cells, selection of a cell of interest in the group, record of the cell location, laser pulse direction to the cell and generation of a discrete loop, discrete loop introduction into the inductively coupled plasma, and generation of groups corresponding to the elementary ion marker, detection of each of the elementary ion groups simultaneously for each discrete loop by means of mass cytometry and correlation of the detected elementary ions with the property of interest. The system includes an interrogator to identify the location of a suitable cell, a data storage for cell location recording, a laser ablation system for laser pulse direction to localize the cell, and a mass cytometer for detection of a marker bound to a suitable cell.

EFFECT: expansion of the cell analysis area as compared to the capabilities of traditional cell-based displaying or imaging techniques.

15 cl, 5 dwg