LIGANDS TO RECEPTOR OF FOLLICLE-STIMULATING HORMONE (FSH) IN DIAGNOSTICS AND TREATMENT OF TUMORS Russian patent published in 2021 - IPC C07K14/59 A61K38/24 A61P35/00 

Abstract RU 2755000 C2

FIELD: medicine.

SUBSTANCE: invention relates to the use of a ligand of a receptor of follicle-stimulating hormone (hereinafter – RFSH) of a human, which is a β-subunit of follicle-stimulating hormone (FSHβ) of a human, and which is characterized by a sequence SEQ. ID. no. 2 or a sequence that is at least 90% similar to the sequence corresponding to SEQ. ID. no. 2, preferably 90-99.9% or more similar, and more preferably 95-97% similar, for the treatment and/or diagnostics of tumors. A method for obtaining the ligand of the receptor of follicle-stimulating hormone (RFSH) of a human, which is a β-subunit of follicle-stimulating hormone (FSHβ) of a human, using recombinant DNA technology, is also proposed. Forms of FSH subunits of the present invention bind to FSHR with high affinity.

EFFECT: producing the ligand of RFSH for the treatment of tumors.

21 cl, 21 dwg

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RU 2 755 000 C2

Authors

Carpi, Andrea

Maset, Fabio

Dal Monte, Renzo

Dates

2021-09-08Published

2017-10-10Filed