METHOD OF PRODUCING 7-IMINO-6-OXABICYCLO [3,2, 1] OCT-3-EN-1,8, 8-TRICARBONITRILES Russian patent published in 2017 - IPC C07D313/02 

FIELD: chemistry.

SUBSTANCE: invention refers to the method of producing functionally substituted condensed heterocyclic molecules containing a imine-laktone fragment and three cyano-groups of -7-imino-6-oxabicyclo[3.2.1]oct-3-en-1.8, 8-tricarbonitriles of the common formula

(1), where R=CH₃ (1a); R=C₂H₅ (1b); R=C₃H₇ (1c); R=C₄H₉ (1d), namely, that the solution of tetracyanoethylene corresponding, α,β-unsaturated aldehyde in equimolar quantities are heated in ethyl acetate at a temperature of 50-55°C in the presence of the catalytic quantities of bromide-hydrogen acid, upon completion of the reaction the solvent is evaporated, the residue is ground in chilled propane-2-ole, the resulting precipitate is filtered.

EFFECT: increasing the yield and use of more environmentally friendly solvent, the resulting compound can be used in fine organic synthesis and as biologically active compounds.

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