COMPOSITION OF PROLONGED ACTION OF CYCLOSPORIN OF FORM 2 Russian patent published in 2017 - IPC A61K9/00 A61K38/13 A61K47/30 A61P27/02 

Abstract RU 2639393 C2

FIELD: pharmacology.

SUBSTANCE: group of inventions is an ophthalmic composition containing cyclosporin A of form 2 and any hydrogel where cyclosporin of form 2 is characterized by peaks when scanned with X-ray diffractometer with the radiation of Cu Kα, 2θ: 7.5, 8.8, 10.2, 11.3, 12.7, 13.8, 14.5, 15.6 and 17.5; as well as a method to treat the condition selected from the following: dry eye syndrome, blepharitis, meibomian gland disease, violation of corneal sensitivity, allergic conjunctivitis, atopic keratoconjunctivitis and pterygium, including a stage of administration of said composition to the patient, who has such a condition.

EFFECT: increased bioavailability, reduced foreign body sensation and achieved high stability.

6 cl, 8 dwg, 3 tbl, 1 ex

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RU 2 639 393 C2

Authors

Blanda Vendi M.

Ettar Mejssa

Dates

2017-12-21Published

2012-11-14Filed