SUSPENSION COMPOSITIONS OF CYCLOSPORINE A FOR SUBCONJUNCTIVAL AND PERIOCULAR INJECTION Russian patent published in 2020 - IPC A61K9/08 A61K38/13 A61K47/36 A61K47/38 A61P27/02 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to ophthalmology, and aims at treating ophthalmic diseases by subconjunctival injection. Suspension composition for subconjunctival injection into human eye contains cyclosporine A; suspending agent; osmosis-regulating agent; one or more buffers; SAS and carrier. Cyclosporine A has particle size D₉₀ in range from 70 mcm to 100 mcm. Invention also provides two-component systems for making said suspension for subconjunctival injection and a system for delivering said suspension composition.

EFFECT: using the group of inventions enables accelerating resorption in subconjunctival administration.

25 cl, 8 dwg, 12 tbl, 9 ex