5-(PYRIDINE-2-YLAMINO)-PYRASIN-2-CARBONITRILE COMPOUNDS AND THEIR THERAPEUTIC APPLICATION Russian patent published in 2018 - IPC C07D401/12 C07D401/14 A61K31/497 A61P35/00 

Abstract RU 2641693 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to compounds of the formula

,

as well as to pharmaceutical compositions based thereon for use in the treatment of a disease or condition mediated by SNK1.

EFFECT: new compounds are obtained that inhibit the kinase function of kinase 1 of the control point.

37 cl, 2 dwg

Similar patents RU2641693C2

Title Year Author Number
5-[[4-[[MORPHOLIN-2-YL]METHYLAMINO]-5-(TRIFLUOROMETHYL)-2-PYRIDYL]AMINO]PYRAZINE-2-CARBONITRILE, THERAPEUTIC USES THEREOF 2013
  • Kollins Yan
  • Mettyus Tomas Piter
  • Fariya Da Fonseka Makkhardi Tatyana
  • Ozborn Dzhejms
  • Lejnchbari Majkl
  • Uolton Majkl Yan
  • Garrett Mishel Doun
RU2659786C2
MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND ANALOGUES THEREOF, PRODUCTION AND USE 2017
  • Ivashchenko Aleksandr Vasilevich
  • Ivashchenko Andrej Aleksandrovich
  • Savchuk Nikolaj Filippovich
  • Mitkin Oleg Dmitrievich
  • Ivashchenko Alena Aleksandrovna
RU2731385C1
QUINAZOLINE INHIBITORS OF ACTIVATING MUTANT FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR 2014
  • Li David Yunzhi
  • Wang Jiabing
  • Yang Zhenfan
  • Zeng Qingbei
  • Zhang Xiaolin
RU2656597C2
EGFR INHIBITOR COMPOUNDS 2017
  • Banker, Kevin Duejn
  • Khuan, Piter Tsinkhua
  • Abrakham, Sanni
  • Pinchman, Dzhozef Robert
  • Khopkins, Chad Deniel
  • Sli, Debora Khelen
RU2751341C2
2-(AZAINDOL-2-YL)BENZIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS 2012
  • Atkinson Stephen John
  • Barker Michael David
  • Campbell Matthew
  • Diallo Hawa
  • Douault Clement
  • Garton Neil Stuart
  • Liddle John
  • Sheppard Robert John
  • Walker Ann Louise
  • Wellaway Christopher
  • Wilson David Matthew
RU2611010C2
DERIVATIVES OF 6-AMINO QUINAZOLINE OR 3-CYANOQUINOLINE, METHODS OF THEIR PRODUCTION AND THEIR APPLICATION AS INHIBITORS OF RECEPTOR TYROZINE KINASES EGFR OR HER-2 2010
  • Tan Pehn Cho
  • Li Sin'
  • Van Bin'
  • Van Tszjun'
  • Chehn' Litszjun'
RU2536102C2
PHTHALAZINE KETONE DERIVATIVE, METHOD OF OBTAINING THEREOF AND PHARMACEUTICAL APPLICATION 2011
  • Tan Pehn Cho
  • Li Sin'
  • Li Sjantsin'
  • Chehn' Jan
  • Van Bin'
  • Chzhu Chzhe
RU2564527C2
SELECTIVE KINASE JAK1 INHIBITOR 2020
  • Qi Changhe
  • Tsui Honchung
  • Zeng Qingbei
  • Yang Zhenfan
  • Zhang Xiaolin
RU2818002C2
NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN 2014
  • Bejr Kennet V.
  • Lancha Devid R.
  • Li Khunbin
  • Lok Dzhejms
  • Lyu Vej
  • Martin Mettyu V.
  • Millan Devid S.
  • Shiller Shon E.R.
  • Tebbe Mark Dzh.
RU2686323C2
NEW DERIVATIVES OF 5, 7-DISUBSTITUTED [1, 3] THIAZOLO[4, 5-D] PYRIMIDINE-2(3H)-ONE 2006
  • Nordvall' Gunnar
  • Rehj Kolin
  • Rejn Tobias
  • Son Dehniel
RU2411245C9

RU 2 641 693 C2

Authors

Kollins Yan

Lejnchbari Majkl

Mettyus Tomas Piter

Rider Dzhon Charlz

Dates

2018-01-22Published

2012-11-09Filed