METHOD FOR CERULOPLASMINE CONCENTRATION PREDICTION FOR TRAINED WORKERS EXPOSED TO MERCURY Russian patent published in 2018 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: method for prediction of ceruloplasmin concentration in trained workers exposed to mercury includes determination of the ceruloplasmin level and gamma-glutamyltransferase activity in the blood serum, the period of work under mercury exposure is calculated 4-5 years after from the current time, and the results of patient examination are substituted into the equation: Y=-3.77665+3.77665+0.31061×GGT₁+0.00518×WORKPERD₂²+2.01893×CP₁-0.02850×CP₁² where Y is the predicted concentration of ceruloplasmin after 4-5 years, -3.77665 is the constant; 0.31061, 0.00518, 2.01893, 0.02850 are predictor coefficients; GGT₁ is the concentration of gamma-glutamyl transferase in the serum at the time of the examination (U/l), not exceeding 200 U/l; CP₁ is the concentration of ceruloplasmin in the serum for the predicted moment (WORKPERD₂ at the moment of examination +4-5 years).

EFFECT: method allows to judge the risk of cardiovascular diseases development and develop a program for their prevention in a timely manner.

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