SALTS OF DASATINIB IN AMORPHOUS FORM Russian patent published in 2018 - IPC C07D417/12 A61K31/506 C07D275/06 

Abstract RU 2655435 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to dasatinib salts in amorphous form. Dasatinib salt contains the cation of a compound of formula 1, known as dasatinib, and the anion of a second compound selected from a group consisting of saccharin, glutaric acid and nicotinic acid.

EFFECT: dasatinib salt of the invention is used as a medicament for the treatment of cancer, particularly chronic myelogenous leukemia and/or acute lymphoblastic leukemia complicated by the Philadelphia chromosome.

7 cl, 3 dwg, 3 tbl, 7 ex

формула 1 - formula 1

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RU 2 655 435 C2

Authors

Khafner Andreas

Blatter Fritts

Shelagevich Martin

Zibenkhaar Bernd

Kiodo Titsiana

Khintermann Tobias

Salvador Beate

Fossen Markus

Dates

2018-05-29Published

2014-07-22Filed