ANTITHROMBOTIC ARTIFICIAL BLOOD VESSEL Russian patent published in 2018 - IPC A61F2/06 A61L27/18 A61L27/54 

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Artificial blood vessel is described, which is a tubular material comprising: a fibre layer containing ultrafine fibre(s), and an ultrafine fibre layer in the inside of the fibre layer, the ultrafine fibre layer being composed of an ultrafine fibre(s) having fibre diameter(s) of not less than 10 nm and not more than 3 mcm, wherein a quaternary ammonium group-containing polymer having alkyl groups in each of which the number of carbon atoms is equal to 4 or less, is covalently bound to the ultrafine fibre(s); heparin is ionically bound to the quaternary ammonium group-containing polymer; and the residual heparin activity after washing with physiological saline at 37°C for 30 minutes is 20 mIU/cm² or more.

EFFECT: artificial blood vessel that promotes intimal formation after indwelling, and is capable of maintaining antithrombogenicity during the intimal formation, and of maintaining its patency for a long time.

8 cl, 1 dwg, 1 tbl, 4 ex