FIELD: chemistry.
SUBSTANCE: invention relates to a process for the preparation of 11-aryl-8,9,13,14-tetraox-11-azaspiro[6.7]tetradecanes of general formula (1):
,
in which o-, m-, p-chloroanilines are reacted with 8,9,11,13,14-pentaoxaspiro[6.7]tetradecane in the presence of a catalyst Sm(NO3)3⋅6H2O at a molar ratio of chloraniline : 8,9,11,13,14-pentaoxaspiro [6.7] tetradecane : Sm(NO3)3⋅6H2O = 10 : (10–12) : (0.5–0.7) at room temperature (20 °C) and atmospheric pressure for 4–6 hours in tetrahydrofuran.
EFFECT: method for the preparation of 11-aryl-8,9,13,14-tetraoxa-11-azaspiro[6.7]tetradecanes of the general formula (1) is obtained in high yield.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING (1S,4R)-1-ISOPROPYL-4-METHYL-10-ARYL-7,8,12,13-TETRAOXA-10-AZASPIRO[5_7]TRIDECANES | 2019 |
|
RU2726405C1 |
| METHOD FOR PREPARING 9-ARYL-6,7,11,12-TETRAOX-9-AZASPHIRO[4.7]DODECANES | 2017 |
|
RU2664646C1 |
| METHOD FOR PREPARATION OF 16-ARYL-6,7,13,14,18,19-HEXAOXA-16-AZADOSPHIRO[4.2.4.7]NONADECANES | 2017 |
|
RU2664651C1 |
| PROCESS FOR THE PREPARATION OF 3,3-DIALKYL-7-ARYL-1,2,4,5,7-TETRAOXAZOCANES | 2017 |
|
RU2664647C1 |
| METHOD OF PRODUCING 2-(8,9,17,18,22,23-HEXAOXA-20-AZADISPIRO[6_2_6_7]TRICOSANE-20-YL)ACETIC ACIDS | 2019 |
|
RU2726126C1 |
| METHOD OF PRODUCING 10-ARYL-7,8,12,13-TETRAOXA-10-AZA-SPIRO[5,7]TRIDECANES | 2014 |
|
RU2584950C1 |
| METHOD OF PRODUCING Α,Ω-DI-(SPIRO[ADAMANTANE-2,3'-[1,2,4,5,7]TETRAOXAZOCANE]-7'-YL)ALKANES | 2019 |
|
RU2727139C1 |
| METHOD FOR PRODUCTION OF 10-HALOPHENYL-7,8,12,13-TETRAOXA-10-AZASPIRO[5_7]TRIDECANES | 2015 |
|
RU2605445C1 |
| METHOD OF PRODUCING PENTAOXASPYROALKANES | 2015 |
|
RU2601315C1 |
| METHOD OF PRODUCING TETRAOXATHIOSPIROALKANES | 2019 |
|
RU2726798C1 |
