FIELD: chemistry.
SUBSTANCE: invention relates to a process for the preparation of 16-aryl-6,7,13,14,18,19-hexaoxa-16-azadispiro[4.2.4.7]nonadecanes of general formula (1):
,
in which anilines (aniline, n-chloroaniline, o-, n-fluoroanilines) are reacted with formaldehyde and 1,1-dihydroperoxycyclohexane in the presence of a catalyst Sm(NO3)3⋅6H2O, taken in the molar ratio of aniline : formaldehyde : 1,1'-peroxybis(1-hydroperoxycyclohexane) : Sm(NO3)3⋅6H2O = 10:20:(10–12):(0.3-0.7) at room temperature (20 °C) and atmospheric pressure for 4–6 hours in tetrahydrofuran.
EFFECT: method for the preparation of 16-aryl-6,7,13,14,18,19-hexaoxa-16-azadospiro[4.2.4.7]nonadecanes of the general formula (1) in high yield.
1 cl, 1 tbl, 1 ex
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