METHOD OF DETERMINING COMPONENTS OF IMPEDANCE OF BIO-OBJECT Russian patent published in 2018 - IPC A61B5/53 G01R27/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, can be used to assess the functional state of the organism. As components of the impedance of the biological object, the active resistance R and the equivalent capacitance C of the bio-object tissues are determined. In this case a stabilized current pulse I₀ is applied to the bioobject and the voltage U_i at time t_i after the start of the current pulse. Maximum value of the potential E is determined from the calibration characteristic. Calibration is carried out a priori for two voltage values: the measured U_i and known reference U_ei, where i=1, 2, at two instants of time t₁ and t₂=2t_1. Calibration characteristic is the function of the maximum value of the potential E_0i compensating for the uncertainty of the T time constant by arbitrarily chosen T* and connecting the reference U_ei and the measured U_i characteristics of the definition of impedance due to the normalization of the measured values by known ones. Further on the values of the lower E₀₁ and upper E₀₂ range limits of the calibration characteristic E_0i find the real values of the T time constant and the maximum value of the potential E , the calibration characteristic E_0i and the real U_∂i characteristic of the definition of impedance are gradually constructed on their bases, said characteristic is maximally close to the reference U_ei=U_∂i. Taking into account the calculated values of E and T, the components of the impedance R and C of the biological object are determined.

EFFECT: method provides an improvement in the accuracy of determining the actual impedance characteristic due to the calibration characteristic compensating for the uncertainty of the time constant selected arbitrarily.

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