RECOMBINANT PLASMID DNA PAL2-T-EXP, USED TO CREATE DNA CALIBRATORS IN EVALUATING THE EFFECTIVENESS OF THERAPY IN PATIENTS WITH ACUTE MYELOID LEUKEMIA Russian patent published in 2018 - IPC C12N15/00 

Abstract RU 2670543 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and medicine, namely to recombinant plasmid DNA pAL2-T-ExP. Plasmid DNA pAL2-T-ExP is designed to create DNA-calibrators in evaluating the effectiveness of therapy in patients with acute myeloid leukemia. This plasmid DNA contains an insert of sequentially cross-linked ligation sites of cDNA genes PRAME, WT1, BAALC, ABL1, GUSB.

EFFECT: invention allows to obtain DNA calibrators for evaluating the effectiveness of therapy with increased accuracy in patients with acute myeloid leukemia.

1 cl, 3 dwg

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RU 2 670 543 C1

Authors

Potter Alisa Yanovna

Barkhatov Ildar Munerovich

Izmajlova Ekaterina Andreevna

Dates

2018-10-23Published

2017-07-26Filed