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2 676 641

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IPC

G09B23/28(2006-01-01)

(21) (22)

Application

2018112353, 2018-04-05

(24)

Start date

2018-04-05

(22)

Actual filing date

2018-04-05

(45)

Published

2019-01-09

(72)

Inventor

Kit Oleg IvanovichFrantsiyants Elena MikhajlovnaKaplieva Irina ViktorovnaTrepitaki Lidiya KonstantinovnaKotieva Inga MovlievnaShalashnaya Elena VladimirovnaIshonina Oksana Georgievna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauchno-Issledovatelskij Onkologicheskij Institut" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD OF STIMULATING CHRONIC PAIN OF MALIGNANT GROWTH IN LUNG RATS Russian patent published in 2019 - IPC G09B23/28

Abstract RU 2676641 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental oncology and can be used to stimulate chronic pain of malignant growth in the lungs of rats. 2 weeks before tumor transplantation, is created a model of chronic pain by bandaging the sciatic nerves on both sides. Inoculation is carried out by introducing into the subclavian vein a suspension of tumor cells of sarcoma M1 in physiological solution in a volume of 0.5 ml and at a dilution of 1:10. Results of the experiment are assessed 1.5–2 months after tumor inoculation.

EFFECT: method provides an effective model of a malignant process in the lungs with high reproducibility due to the additional effect of chronic pain during the transplantation of tumor cells.

1 cl, 1 tbl

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RU 2 676 641 C1

Authors

Kit Oleg Ivanovich

Frantsiyants Elena Mikhajlovna

Kaplieva Irina Viktorovna

Trepitaki Lidiya Konstantinovna

Kotieva Inga Movlievna

Shalashnaya Elena Vladimirovna

Ishonina Oksana Georgievna

Dates

2019-01-09—Published

2018-04-05—Filed