FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to a medium composition for the production of botulinum toxin and, more specifically, to a medium composition for culturing Clostridium sp., which is capable of producing botulinum toxin. Medium compositions of the present invention include a porcine peptone and at least one plant-derived peptone selected from the group consisting of a garden pea hydrolysate, a cotton seed hydrolysate and a wheat gluten hydrolysate. When the medium according to the present invention, which contains plant-derived peptones, porcine peptones and minerals, is used to culture Clostridium botulinum, the growth rate of the bacterium in the medium is higher than that in the medium in current use. which includes only plant-derived peptones.
EFFECT: invention allows to obtain a high concentration of botulinum toxin.
8 cl, 12 dwg, 16 tbl, 10 ex
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