TOXIN PRODUCTION METHOD Russian patent published in 2023 - IPC C12N1/20 C12P21/02 C07K14/33 

Abstract RU 2789552 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a method for production of botulinum toxin. The proposed method includes the production of botulinum toxin by cultivation of Clostridium botulinum type A in a composition of a medium for cultivation of Clostridium botulinum type A and extraction of botulinum toxin. At the same time, the medium for cultivation of Clostridium botulinum type A contains from 2 to 5 wt./vol.% of potato peptone, from 0.5 to 2 wt./vol.% of yeast extract, and from 0.75 to 1.5 wt./vol.% of glycose.

EFFECT: invention allows for achievement of the maximum level of toxin formation and the maximum level of culture growth during a short time, thereby providing reduction in cultivation time.

4 cl, 7 dwg, 13 tbl, 5 ex

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RU 2 789 552 C1

Authors

Kim, Dzhe Eun

Nam, Dzhon Sun

Kim, Seunkho

Kim, Mindzhoon

Li, Vonil

Yun, Bum Dzhin

Dates

2023-02-06Published

2020-03-12Filed