TRICYCLIC GYRASE INHIBITORS Russian patent published in 2019 - IPC C07D487/04 C07D487/14 C07D471/14 A61K31/519 A61P31/04 

Abstract RU 2680138 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel compound of formula I and its pharmaceutically acceptable salts. Said compounds possess antibacterial activity and can be used in treatment of bacterial infections. In formula I , the values of the radicals R2, R4, L are selected from the following values:

.

EFFECT: compounds have improved activity compared with the closest analogues when administered orally while maintaining gram-negative activity.

8 cl, 4 tbl, 5 ex

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Authors

Finn Dzhon

Tari Lesli Uillyam

Chen Chzhiyun

Chzhan Tszyunkhu

Fillipson Duglas

Li Suk Dzoong

Trtsoss Majkl

Bensen Deniel

Li Syaomin

Ten Min

Ong Voon

Borkhardt Allen Dzhon

Lam Tkhan To

Lajtstoun Filis S.

Vong Serdzho I.

Ngujen Toan B.

Dates

2019-02-18Published

2014-09-10Filed