SOLID PHARMACEUTICAL FORM OF INDOLE-3-CARBINOL Russian patent published in 2019 - IPC A61K31/404 A61K47/12 A61K47/02 A61K47/26 A61K47/36 A61K47/38 A61K9/48 A61P35/00 

Abstract RU 2680967 C2

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to the pharmaceutical industry in particular to a pharmaceutical composition having anti-tumor activity. Pharmaceutical composition is proposed, in the form of solid capsules of two formulations based on micronized indole-3-carbinol and auxiliary substances in the following ratios, g/capsule: indole-3 carbinol 0.15–0.200, lactose 0.110–0.140, microcrystalline cellulose 0.034–0.064, corn starch modified Starch 1500 0.06–0.095, salts of stearic acid calcium or magnesium – 0.001–0.04, sodium starch glycolate – 0.03–0.05 or croscarmellose sodium – 0.030–0.004.

EFFECT: implementation of the invention provides the preparation of a medicament that increases the therapeutic efficacy of indole-3-carbinol by increasing bioavailability.

4 cl, 1 dwg, 4 ex, 3 tbl

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RU 2 680 967 C2

Authors

Kisilev Aleksej Pavlovich

Rogova Natalya Viktorovna

Dates

2019-03-01Published

2017-04-11Filed