FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to the pharmaceutical industry in particular to a pharmaceutical composition having anti-tumor activity. Pharmaceutical composition is proposed, in the form of solid capsules of two formulations based on micronized indole-3-carbinol and auxiliary substances in the following ratios, g/capsule: indole-3 carbinol 0.15–0.200, lactose 0.110–0.140, microcrystalline cellulose 0.034–0.064, corn starch modified Starch 1500 0.06–0.095, salts of stearic acid calcium or magnesium – 0.001–0.04, sodium starch glycolate – 0.03–0.05 or croscarmellose sodium – 0.030–0.004.
EFFECT: implementation of the invention provides the preparation of a medicament that increases the therapeutic efficacy of indole-3-carbinol by increasing bioavailability.
4 cl, 1 dwg, 4 ex, 3 tbl
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Authors
Dates
2019-03-01—Published
2017-04-11—Filed